Can ZFS be used in 22.04?

have 4 drives, two M2 drives and two SSDs. I would like to take the 2nd M2 drive and the two SSDs and make them a ZFS pool. I do not want to touch the book drive, that stays ext4.

In 22.04 can I mix file system types? an I mix NVM and SDD in a ZFS pool? Is ZFS part of the kernel? Can a missed update cause a loss of data drives?

Thanks, Doug