How to edit tooltips and application names for applications without .desktop file?

I'm developing a graphical application with PyDM. The application is spawned by just executing its .py file, so it has no .desktop file.

For some reason, the interaction between PyDM and PyQT seems to override the PyQT ApplicationName methods and properties, so I can't dynamically or even statically define it via python code in any way I could think of.

So I'm now searching for a "Ubuntonic" instead of a pythonic way of changing the tooltip that shows when you hover your mouse above the application icon:

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All solutions I found until now involve modifying its .desktop file, which is something I can't do for several reasons. Is there any other way to do this?

Solutions I found until now:

• How can I edit tooltips for unity launcher icons?

• How to safely change the names of items in the system settings