After an upgrade to 11.10 (kernel: Linux lucid 3.0.0-13-generic #22-Ubuntu) which probably also updated Skype to 2.2.35 (not sure because I never checked the version before) the sound that comes back from an echo test is very high pitched and squeaky. I'm not sure if when in a call if the other person can't hear or just doesn't know what they are hearing. I am using a USB Logitech C250
Audacity records fine, gmail video chat works fine, but if I start sound recorder I get a "Could not negotiate format", followed by "Could not get/set settings from/on resource". I don't know if this is a Skype problem or a wider Pulse problem.
My only real needs are the gmail and Audacity, though I have a couple of contacts that I can only Skype with.
There is a bug open in Launchpad (have a look here)
Comment #80 helped me:
I had slightly different problem with Skype, but the solution might be the same.
Why can't Skype hear me?