Will an Ubuntu install with Nvidia drivers boot properly on a system with an AMD GPU?

So, I love having an external HDD with Ubuntu on it and bring able to boot it on any computer and be right at home in Linux with all my files and programs.

Now here's my question: if I install the Nvidia drivers, will it only boot properly on a system with an Nvidia GPU, or will it still work just fine on systems with an Intel or AMD GPU?

Normally I would just try it and see what happens, but I would prefer not to screw up my drive and have to spend a few hours fixing it. (I've already nuked one Ubuntu install beyond repair when messing with the Nvidia drivers about a year ago)