What are the main differences between desktop-series hard disks and server-series?
The obvious things I can see are: durability (server hardware mostly more qualitative and have more warranty) and power consumption (server hardware more focused on performance, than on power economy). Also server disks are usually a little faster, but it seems, that it is not always the case.
May be there are some other reasons, that make you choose server-oriented series (Seagate ES drives, for example) over desktop-oriented ones (Seagate Barracuda series)? What are they?
One very important difference is the Time-Limited Error Recovery (aka Command Completion Time Limit)
This is very important in RAID arrays where one drive can lock up or degrade the array.
According to Intel's Enterprise-class versus Desktop-class Hard Drives, enterprise-class drives are often faster and more reliable due to better hardware and different firmware.
Better hardware specs:
Behavior:
Testing:
Warranty:
Nonetheless, the issue about TLER might be the main reason for choosing server-grade storage solutions over consumer products, especially when operating RAID systems and servers with time-critical workloads like web or database servers.
Other than that, yes, there is probably some FUD by the manufacturers to make you feel uneasy about using desktop products for a server, so using enterprise products will also give you some peace of mind.
THE most important difference is the level of Vendor Support.
If you don't use "hardware compatible" equipment (i.e. OEM) then you may find yourself SOL when the kit dies and you need to get it fixed quick.
Enterprise hard disks also tend to have a longer MTBF (Mean Time Between Failures), i.e. longer life span, than consumer grade ones.
The heat-pad under a smooth chip (motor controller) is missing in the most of the consumer drives (seagate, WD), but is usually present in the most of the enterprise class disks. (so the tiny smooth chip is much more likely to die under the load from overheat in the desktop model). Also enterprise drives usually have a couple of the vibration sensors. Rubber anti vibration dumpers and rigid cases are strongly recommended for all modern high density disks/fan mounts. (Esp ones over with density 500GB+ per platter, since their heads are really fragile from my experience).
Two things:
Reliability is not a distinguishing factor.