When we try to open a document from SharePoint we get a message box with the message "Could not open [docpath]". If we copy the path into word we can access the document. After some seaching on the net we found that if you reset the advanced setting in IE 6 then it sould work, but we did not find what setting that made it not work.
So what setting in IE 6 makes it so that we can't open word document directly in SharePoint 2007?
can you confirm that you've configured the MIME types in IIS as application/msword for .doc & .docx extensions?
Is there something that is blocking your access to the document? For example urlscan?