How to configure Apache mod_proxy to select a URL from a table? E.g. via a script?

We've got Apache mod_proxy performing the function of a reverse proxy to a specific host:ip currently.

We would like to be able to take a url like https://domain/pathA and https://domain/pathB and look up the appropriate host:port in a table or via an HTTP rest service call. Each pathX will have a different place the proxy should get the information from.

We would like to avoid hard coding this information into the Apache config because it will change often.