I don't think there's any way to do this after looking through Microsoft's password policy documentation, but on the off-chance that someone was particularly clever:
Is it possible to create a policy so that only business days count towards password expiration? The idea being that a password that expired on Saturday would not necessitate a helpdesk call until Monday, and VPN users would be able to continue to get in.
We're Server 2008 R2 here. The best workaround I can come up with is to enable this in Outlook Web Access:
https://technet.microsoft.com/en-us/library/bb684904
But not sure how this will play with our Duo two-factor.
I'm open to third-party stuff if that will work. I don't see this as a PowerShell opportunity, but tell me if I'm wrong.