I'm looking to setup a cookie-free domain intended to serve static content for a web application, similar to the http://sstatic.net/ site that the stack exchange sites use.
My question is, what optimizations can I make to my IIS 7.5 setup for such a domain? For example, it will never be responsible for anything but serving static content, so would disabling ASP.NET integration be a good move for this site?
Any suggestions or references on setting up such a site with IIS 7.5 would be most welcome.
Edit
Just to clarify, this isn't the ONLY site on the server, so suggested optimizations should target the site level, and not the server-level config.