We are generally running php 5.4.x with APC enabled on CENTOS for our production sites. We have a new app that is segfaulting and the development team thinks it is because we've got APC. The app is complicated and really needs an opcode cache.
We have a number of existing apps happily using APC for their opcode and other caching needs that we don't really want to QA so what we'd love to do is just install the OpCache extension along side the APC extension and then let apps enable or disable as they will. I cannot, however, find any indication this will or won't work so before we get to messing with chef to make this happen I'd love to get some insight on that.